Cognition and Neuroimaging in Females with Autism Spectrum Conditions

This project is a follow-up study of the MRC Autism Imaging Multicentre Study (AIMS). The latter focused exclusively on males, and this follow-up focuses exclusively on females with ASC. This is because females with ASC are a neglected group in ASC research. The study is scanning female adults with Asperger Syndrome (AS) or high functioning autism (HFA) and age-matched female controls using structural MRI, resting and task fMRI, and diffusion tensor imaging (DTI). Participants also undergo a set of comprehensive cognitive and behavioural assessments. The study is being conducted in collaboration with Prof. Declan Murphy and Dr. Michael Craig at the Institute of Psychiatry, London.



Selected References

596: A Ruigrok, G Salimi-Khorshidi, M-C Lai, S Baron-Cohen, M Lombardo, R Tait, J Suckling (2014)
A meta-analysis of sex differences in human brain structure
Neuroscience and Biobehavioral Reviews 39:34-50

559: M-C Lai, M Lombardo, J Suckling, A Ruigrok, B Chakrabarti, C Ecker, S Deoni, M Craig, D Murphy, E Bullmore, MRC AIMS Consortium, S Baron-Cohen (2013)
Biological sex affects the neurobiology of autism
Brain 136:2799-2815

541: M-C Lai, M V Lombardo, A N Ruigrok, B Chakrabarti, S J Wheelwright, B Auyeung, C Allison, S Baron-Cohen (2012)
Cognition in Males and Females with Autism: Similarities and Differences
PLoS ONE 7(10):e47198

508: M. Lai, M. Lombardo, G. Pasco, A. Ruigrok, S. Wheelwright, S. Sadek, B. Chakrabarti, MRC AIMS Consortium, S. Baron-Cohen (2011)
A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum Conditions
PLoS ONE 6(6):e20835

399: R. Knickmeyer, S. Wheelwright and S. Baron-Cohen (2008)
Sex-typical Play: Masculinization/Defeminization in Girls with an Autism Spectrum Condition
Journal of Autism and Developmental Disorders 38:1028-1035

375: E. Ingudomnukul, S. Baron-Cohen, S. Wheelwright and R. Knickmeyer (2007)
Elevated rates of testosterone-related disorders in women with autism spectrum conditions
Hormones and Behavior 51:597-604

365: R. Knickmeyer, S. Baron-Cohen, R. Hoekstra and S. Wheelwright (2006)
Age of menarche in females with autism spectrum conditions
Developmental Medicine & Child Neurology 48:1007-1008

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