Aicha is studying the autistic brain using induced pluripotent stem cells (iPSC) as a model system. She is modelling neuronal development and gene expression in the autistic brain, with a particular interest in the effects of mutations in the NRXN1 gene, and how foetal androgens and oestrogens affect methylation in genes expressed in the autistic brain.
She is co-supervised by Dr Deepak Srivastava, Director of the Centre for the Cellular Basis of Behaviour at King’s College London (KCL), Dr Mark Kotter at the Laboratory of Regenerative Medicine (LRM), Cambridge, and Professor Simon Baron-Cohen. Her advisors include Dr Deep Adhya at KCL/ARC and Dr Jason Carroll at Cancer Research UK in Cambridge. She collaborates with KCL and with the University of Pennsylvania.
Prior to coming to Cambridge she completed an MSc in Biotechnology at the University of Greenwich, a BSc in Biotechnology at the University for Modern Science and Arts, Egypt, where she was also Assistant Lecturer and Teaching Assistant. She was also Research Assistant in the Breast Cancer Lab at Cairo University and the National Cancer Institute, Egypt.
She is funded by the Cambridge Commonwealth European and International Trust Yousef Jameel Scholarship, and the Autism Research Trust.
- Environmental Pressures on Transgenerational Epigenetic Inheritance, (2020), D Adhya, A Massrali, A Paul, M Kotter, J Carroll, D Srivastava, J Price, S Baron-Cohen
- Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits, Molecular Autism 10, 31 (2019), A Massrali, H Brunel, E Hannon, C Wong, S Baron-Cohen, V Warrier
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